本中心目前非SPF等級飼育室(603、617、618、619、621及646室) ，經長年動物監測結果，皆帶有 SPF列管的病原且檢出率高。經與獸醫師討論後，建議採用半屏蔽系統的二級清潔動物*的飼養方式：仍使用 Biozone IVC (可有效隔離避免籠間汙染) 及laminar flow (可降低病原於動物房內散佈風險) 進行動物飼養及實驗操作，惟不使用滅菌的籠具。
自113年1月1日起執行措施如下
1.不使用滅菌的籠具(含墊料)進行飼養。
2.動物照養及操作仍維持在laminar flow中進行，以維持飼育室內的潔淨。
3.滅菌飼料仍持續提供至113年6月底，以避免影響目前執行中的實驗。若須延長期限，到時請與動物中心提出需求。
若有任何問題歡迎與本中心聯絡。
*二級清潔動物：除普通級動物應排除的病原外，不攜帶對動物危害大和對科學研究干擾大的病原。來源於SPF動物或剖腹產動物，一般飼養於半屏障系統。
Non SPF grade breeding rooms of LAC include Rooms 603, 617, 618, 619, 621 and 646. According to long-term animal monitoring results, the animals contain SPF-listed pathogens and the detection rate is high. After discussion with the veterinarian, it is recommended to adopt a semi-shielded system for secondary clean degree of animals*. LAC use Biozone IVC machines (which can effectively isolate and avoid contamination between cages) and laminar flow (which can reduce the risk of pathogens spreading in the animal room) still. But animal rearing and experimental operations will not use sterilized cages.
The following measures will be implemented from January 1, 2024
- Do not use sterilized cages (including bedding) for breeding.
- Animal care and operation are still carried out in laminar flow to maintain cleanliness in the breeding room.
- Sterilized feed will continue to be provided until the end of June 2024 to avoid affecting the performing experiments. If the deadline needs to be extended, please inform the animal center at that time.
If you have any questions, please feel free to contact our center.
*Level 2 clean animals:
They do not carry pathogens that are harmful to animals and interfere with scientific research except for the pathogens that should be eliminated by ordinary-level animals. They generally are reared in semi-barrier systems, which are derived from SPF animals or caesarean section animals.
